- rft-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables riboflavin transmembrane transporter activity. Involved in embryo development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A2 (solute carrier family 52 member 2) and SLC52A3 (solute carrier family 52 member 3).
- rft-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables riboflavin transmembrane transporter activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Brown-Vialetto-Van Laere syndrome 1; Brown-Vialetto-Van Laere syndrome 2; and Fazio-Londe disease. Is an ortholog of human SLC52A1 (solute carrier family 52 member 1); SLC52A2 (solute carrier family 52 member 2); and SLC52A3 (solute carrier family 52 member 3).
- mr [Search on AGR]
Drosophila melanogaster morula (mr) encodes the APC2 subunit of the anaphase promoting complex (APC). mr strong alleles produce lethality, metaphase arrest and neuroblast polyploidy. mr weak alleles result in female sterility, affecting the endocycle in the nurse cells, as well as metaphase arrest in early embryonic mitoses.
- brwd [Search on AGR]
Mus musculus PHENOTYPE: Mutant mice have a brown coat color. [provided by MGI curators]
- Bola3 [Search on AGR]
Mus musculus PHENOTYPE: Mice in which the gene is deleted in fat tissue, show impaired glucose tolerance, impaired norepinephrine-induced brown adipose tissue thermogenesis, increased weight gain at thermoneutral temperature and decreased brown adipose tissue glucose uptake [provided by MGI curators]
- Prr30 [Search on AGR]
Homo sapiens ASSOCIATED WITH Tatton-Brown-Rahman syndrome; INTERACTS WITH aflatoxin B1; benzo[a]pyrene; valproic acid
- Rgsc798 [Search on AGR]
Mus musculus PHENOTYPE: Mice with a mutation of this gene have brown fur. [provided by MGI curators]
- Metrnl [Search on AGR]
Homo sapiens Predicted to enable hormone activity. Predicted to be involved in several processes, including brown fat cell differentiation; energy homeostasis; and positive regulation of brown fat cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
- Tmem26 [Search on AGR]
Homo sapiens This gene encodes a protein containing multiple transmembrane helices. It is a selective surface protein marker of brite/beige adipocytes, which may coexist with classical brown adipocytes in brown adipose tissue. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]
- Ccdc121 [Search on AGR]
Homo sapiens ASSOCIATED WITH Tatton-Brown-Rahman syndrome; INTERACTS WITH 17beta-estradiol; 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol