Expressed in head. Is an ortholog of human BLTP3A (bridge-like lipid transfer protein family member 3A) and BLTP3B (bridge-like lipid transfer protein family member 3B). Human BLTP3B enables GARP complex binding activity; lipid transfer activity; and protein homodimerization activity.
Predicted to enable RNA binding activity. Located in cytosol; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Enables Hsp70 protein binding activity. Located in cytosol; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Predicted to enable protein homodimerization activity. Predicted to be located in cytoplasm and intercellular bridge. [provided by Alliance of Genome Resources, Apr 2022]
PHENOTYPE: Homozygotes for this spontaneous mutation have a short face with broad nasal bridge and short snout and a belly spot. [provided by MGI curators]
Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in chromosome; intercellular bridge; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]
Predicted to enable protein kinase binding activity. Predicted to be involved in several processes, including intercellular bridge organization; mitotic spindle assembly checkpoint signaling; and nuclear chromosome segregation. Predicted to act upstream of or within cellular response to leukemia inhibitory factor and negative regulation of cytokinesis. Predicted to be located in cytoplasm. Predicted to be active in intercellular bridge; kinetochore; and midbody. Human ortholog(s) of this gene implicated in spermatogenic failure 23. Orthologous to human TEX14 (testis expressed 14, intercellular bridge forming factor); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 3',5'-cyclic AMP; allethrin.