odr-6

Caenorhabditis elegans

Pkp4

Mus musculus

PHENOTYPE: An uncharacterized gene trap insertion does not result in an obvious phenotype during the observation period early in life, although abnormalities may still develop at older age. [provided by MGI curators]

Cbx1

Mus musculus

PHENOTYPE: An uncharacterized gene trap insertion does not result in an obvious phenotype during the observation period early in life, although abnormalities may still develop at older age. [provided by MGI curators]

sif

Drosophila melanogaster

still life (sif) encodes a guanine nucleotide exchange factor for Rho family GTPases. It is specifically localized to presynaptic terminals in both the central nervous system and neuromuscular junctions (NMJs), and regulates synaptic growth at NMJs.

Ifitm5

Mus musculus

PHENOTYPE: Homozygous null mice exhbit smaller skeletons, partial prenatal and postnatal lethality, and small litter sizes. Mice that survive to adulthood still exhibit shorter bones but other skeletal defects are no longer seen. [provided by MGI curators]

Slc19a1

Mus musculus

PHENOTYPE: Homozygous null embryos die due to abnormalities of hematopoietic organs. Mutant mice may be partially rescued with maternal folic acid supplementation, but these mice still present with hematopoietic organ defects and show impaired development of urogenital structures. [provided by MGI curators]

Cd28

Mus musculus

PHENOTYPE: Homozygous mutation of this gene results in impairment of some T cell responses and decreased basal immunoglobulin levels. Mutant animals have reduced T helper cell activity and impaired T cell response to lectins, but cytotoxic T cells can still be induced. [provided by MGI curators]

UQCRHL

Homo sapiens

This gene has characteristics of a pseudogene derived from the UQCRH gene. However, there is still an open reading frame that could produce a protein of the same or nearly the same size as that of the UQCRH gene, so this gene is being called protein-coding for now. [provided by RefSeq, Jul 2008]

gon-4

Caenorhabditis elegans

Predicted to enable transcription coregulator activity. Involved in gonad development and positive regulation of cell division. Located in germ cell nucleus. Expressed in germ line and gonad. Is an ortholog of human GON4L (gon-4 like) and YY1AP1 (YY1 associated protein 1).

xbp-1

Caenorhabditis elegans

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of transcription by RNA polymerase II; and response to stress. Acts upstream of with a positive effect on negative regulation of multicellular organismal process. Predicted to be located in nucleus. Expressed widely. Is an ortholog of human XBP1 (X-box binding protein 1).