rba-1

Caenorhabditis elegans

Predicted to enable histone binding activity. Involved in cell fate specification; nematode male tail tip morphogenesis; and regulation of neurogenesis. Predicted to be located in nucleus. Predicted to be part of ESC/E(Z) complex and NuRD complex. Is an ortholog of human RBBP7 (RB binding protein 7, chromatin remodeling factor).

ZK673.4

Caenorhabditis elegans

Predicted to enable metal ion binding activity.

F19F10.11

Caenorhabditis elegans

Predicted to be involved in negative regulation of vulval development.

Y32B12B.4

Caenorhabditis elegans

Predicted to be involved in negative regulation of vulval development.

ets-6

Caenorhabditis elegans

Predicted to be involved in negative regulation of vulval development.

lin-35

Caenorhabditis elegans

Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of cell cycle; negative regulation of vulval development; and positive regulation of brood size. Located in nucleus. Expressed in several structures, including head and tail. Used to study intellectual disability. Human ortholog(s) of this gene implicated in several diseases, including germ cell cancer (multiple); high grade glioma (multiple); and urinary system cancer (multiple). Is an ortholog of human RBL1 (RB transcriptional corepressor like 1) and RBL2 (RB transcriptional corepressor like 2).

B0336.7

Caenorhabditis elegans

Predicted to enable DNA binding activity. Expressed in intestine and neurons.

rbpl-1

Caenorhabditis elegans

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in nucleus. Expressed in intestine; neurons; spermatheca; and vulva. Is an ortholog of human RBBP6 (RB binding protein 6, ubiquitin ligase).

lin-53

Caenorhabditis elegans

Enables histone deacetylase binding activity. Involved in several processes, including cell fate specification; embryonic digestive tract morphogenesis; and nematode male tail tip morphogenesis. Acts upstream of or within mitochondrial unfolded protein response. Located in nucleus. Part of DRM complex and NuRD complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P7.p hermaphrodite; and P8.p hermaphrodite. Is an ortholog of human RBBP4 (RB binding protein 4, chromatin remodeling factor) and RBBP7 (RB binding protein 7, chromatin remodeling factor).

mcd-1

Caenorhabditis elegans

Predicted to enable metal ion binding activity. Involved in nematode larval development; positive regulation of growth rate; and programmed cell death.