5 Genes found (0.008 seconds)

algn-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]

Caenorhabditis elegans

Predicted to enable mannosyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ik. Is an ortholog of human ALG1 (ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase).

smu-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]

Caenorhabditis elegans

Involved in several processes, including mechanosensory behavior; nematode larval development; and regulation of alternative mRNA splicing, via spliceosome. Located in nucleolus. Expressed widely. Is an ortholog of human IK (IK cytokine).

Ik [Search on AGR]

Rattus norvegicus

Predicted to enable identical protein binding activity. Predicted to be involved in mRNA splicing, via spliceosome; mitotic spindle assembly checkpoint signaling; and protein localization to kinetochore. Predicted to be located in mitotic spindle pole; nuclear chromosome; and nuclear speck. Predicted to be part of U2-type precatalytic spliceosome. Predicted to be active in nucleus. Orthologous to human IK (IK cytokine); INTERACTS WITH 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Alg1 [Search on AGR]

Homo sapiens

The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik. [provided by RefSeq, Dec 2008]

Alg1 [Search on AGR]

Rattus norvegicus

Predicted to enable chitobiosyldiphosphodolichol beta-mannosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to act upstream of with a positive effect on protein N-linked glycosylation. Predicted to be located in endoplasmic reticulum and membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ik. Orthologous to several human genes including ALG1 (ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.