R07E3.1

Caenorhabditis elegans

Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSW (cathepsin W).

R09F10.1

Caenorhabditis elegans

Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSW (cathepsin W).

Y51A2D.8

Caenorhabditis elegans

Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Is an ortholog of human CTSW (cathepsin W).

ubc-16

Caenorhabditis elegans

Predicted to enable ubiquitin conjugating enzyme activity. Involved in protein ubiquitination. Predicted to be located in nucleus. Expressed in germ line and oocyte. Is an ortholog of human UBE2W (ubiquitin conjugating enzyme E2 W).

npr-32

Caenorhabditis elegans

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of human NPBWR1 (neuropeptides B and W receptor 1).

F55H12.7

Caenorhabditis elegans

Enriched in G2 and W cell based on single-cell RNA-seq studies. Is affected by several genes including swsn-1; cua-1; and etr-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including stavudine; Psoralens; and allantoin based on RNA-seq studies.

ZC518.8

Caenorhabditis elegans

Enriched in G2; W cell; and sensory neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including etr-1; egl-43; and adr-1 based on RNA-seq studies. Is affected by four chemicals including metformin; Sirolimus; and rifampin based on RNA-seq studies.

Y43F8B.22

Caenorhabditis elegans

Enriched in ASER; G2; PLM; and W cell based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including spr-5; xpf-1; and npr-8 based on RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and metformin based on RNA-seq and microarray studies.

flp-33

Caenorhabditis elegans

Enriched in G2; W cell; and neurons based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including mut-16; atfs-1; and etr-1 based on RNA-seq; microarray; and proteomic studies. Is affected by nine chemicals including 1-methylnicotinamide; rotenone; and D-glucose based on RNA-seq studies.

dys-1

Caenorhabditis elegans

Predicted to enable actin binding activity and zinc ion binding activity. Involved in several processes, including forward locomotion; muscle cell cellular homeostasis; and sarcomere organization. Located in striated muscle dense body. Part of dystrobrevin complex. Expressed in body wall musculature; head muscle; pharyngeal muscle cell; and vulval muscle. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in several diseases, including Becker muscular dystrophy; Duchenne muscular dystrophy; cognitive disorder; dilated cardiomyopathy (multiple); and ovarian cancer. Is an ortholog of human DMD (dystrophin) and UTRN (utrophin).