- barr [Search on AGR]
Drosophila melanogaster barren (barr) encodes a chromatin binding protein involved in chromatin condensation. It regulates Malpighian tubule development and epithelial morphogenesis.
- Lrif1 [Search on AGR]
Homo sapiens Predicted to enable retinoic acid receptor binding activity. Involved in dosage compensation by inactivation of X chromosome. Located in Barr body; centriolar satellite; and nucleoplasm. Colocalizes with chromosome, telomeric region. [provided by Alliance of Genome Resources, Apr 2022]
- ZK686.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in protein N-linked glycosylation via asparagine. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Used to study bacterial infectious disease. Human ortholog(s) of this gene implicated in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia; autosomal recessive intellectual developmental disorder 7; and congenital disorder of glycosylation Icc. Is an ortholog of human MAGT1 (magnesium transporter 1) and TUSC3 (tumor suppressor candidate 3).
- Cap-D2 [Search on AGR]
Drosophila melanogaster CAP-D2 condensin subunit (Cap-D2) encodes a component of the conserved condensin I complex, together with the products of Cap-G, barr, SMC2 and glu. Condensin I associates with mitotic chromatin and plays a crucial role in shaping mitotic chromosomes and in their faithful segregation during anaphase.
- Cr2 [Search on AGR]
Homo sapiens This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
- Ebi3 [Search on AGR]
Homo sapiens This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq, Sep 2008]
- HMHB1 [Search on AGR]
Homo sapiens This gene encodes one of the minor histocompatibility antigens, which play an important role in the induction of cytotoxic T lymphocyte (CTL) reactivity against leukemia after human histocompatibility leukocyte antigen (HLA)-identical allogeneic bone marrow transplantation (BMT). This gene is only expressed in B cell acute lymphoblastic leukemia cells and Epstein-Barr virus-transformed B cells. The translation of this mRNA initiates at a non-AUG (CUG) codon. [provided by RefSeq, Jul 2008]
- Rbpjl [Search on AGR]
Homo sapiens This gene encodes a member of the suppressor of hairless protein family. A similar protein in mouse is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signaling pathway transcription factor recombining binding protein J. The mouse protein has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Ebi3 [Search on AGR]
Rattus norvegicus Predicted to enable cytokine binding activity; cytokine receptor activity; and interleukin-27 receptor binding activity. Predicted to be involved in T cell proliferation and cytokine-mediated signaling pathway. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Biomarker of pre-eclampsia. Orthologous to human EBI3 (Epstein-Barr virus induced 3); PARTICIPATES IN interleukin-27 signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
- Ncaph [Search on AGR]
Homo sapiens This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]