- ast-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including nematode pharynx morphogenesis; neuron differentiation; and regulation of nematode male tail tip morphogenesis. Located in nucleus. Expressed in intestine; neurons; and rectal gland cell. Human ortholog(s) of this gene implicated in several diseases, including hereditary lymphedema; pulmonary venoocclusive disease; and thrombocytopenia. Is an ortholog of human FLI1 (Fli-1 proto-oncogene, ETS transcription factor).
- npr-41 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is an ortholog of human GPR142 (G protein-coupled receptor 142).
- mth-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in X-linked congenital bilateral absence of vas deferens and vibratory urticaria. Is an ortholog of human ADGRE2 (adhesion G protein-coupled receptor E2); ADGRG2 (adhesion G protein-coupled receptor G2); and ADGRG7 (adhesion G protein-coupled receptor G7).