Btnt2

Mus musculus

PHENOTYPE: Mice heterozygous for this phenotypic allele exhibit tan bellies. [provided by MGI curators]

Btnt

Mus musculus

PHENOTYPE: Heterozygotes for this spontaneous mutation exhibit a tan colored coat on the belly. [provided by MGI curators]

t

Drosophila melanogaster

tan (t) encodes a hydrolase involved in both the conversion of N-beta-alanyldopamine to dopamine in the cuticle and central nervous system, and the conversion of beta-alanylhistamine (carcinine) to histamine in the retina. It functions in vision, cuticular melanization, and neurotransmitter recycling.

Sar1b

Homo sapiens

The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]