Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleus. Is an ortholog of human KHNYN (KH and NYN domain containing); N4BP1 (NEDD4 binding protein 1); and NYNRIN (NYN domain and retroviral integrase containing).
Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be located in cytoplasmic ribonucleoprotein granule and nucleus. Is an ortholog of human KHNYN (KH and NYN domain containing); N4BP1 (NEDD4 binding protein 1); and NYNRIN (NYN domain and retroviral integrase containing).
Predicted to enable RNA binding activity. Predicted to be located in cytoplasm. Expressed in head. Is an ortholog of human ANKHD1 (ankyrin repeat and KH domain containing 1); ANKHD1-EIF4EBP3 (ANKHD1-EIF4EBP3 readthrough); and ANKRD17 (ankyrin repeat domain 17).
This gene encodes a member of a family of proteins with two K homology (KH) RNA-binding domains and a C-terminal RING-finger domain. The protein interacts with mRNA via the KH domains, and the protein shuttles between the nucleus and cytoplasm. Polymorphisms in this gene may contribute to hypertension. [provided by RefSeq, Oct 2009]
Predicted to be a structural constituent of ribosome. Predicted to be involved in positive regulation of apoptotic signaling pathway. Predicted to be located in nucleus. Predicted to be part of cytosolic small ribosomal subunit. Is an ortholog of human RPS3 (ribosomal protein S3).
Enables mRNA 3'-UTR binding activity; mRNA 5'-UTR binding activity; and single-stranded RNA binding activity. Involved in several processes, including oocyte fate determination; positive regulation of reproductive process; and regulation of gene expression. Located in P granule and cytosol. Expressed in body wall musculature; germ line; neurons; ventral nerve cord; and in male. Is an ortholog of human QKI (QKI, KH domain containing RNA binding).
Essential nucleolar protein required for pre-18S rRNA processing; interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain
The protein encoded by this gene belongs to the KHDC1 family, members of which contain an atypical KH domain that may not bind RNA like canonical KH domains. This gene is specifically expressed in the oocytes, and recent studies suggest that it may function as a regulator of genomic imprinting in the oocyte. Mutations in this gene are associated with recurrent biparental complete hydatidiform mole. [provided by RefSeq, Dec 2011]
Predicted to enable RNA binding activity. Predicted to be active in cytoplasm. Orthologous to several human genes including KHDC1L (KH domain containing 1 like); INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); aflatoxin B1 (ortholog).
Predicted to enable RNA endonuclease activity and mRNA binding activity. Predicted to be active in cytoplasmic ribonucleoprotein granule and nucleus. Orthologous to human KHNYN (KH and NYN domain containing); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.