rrc-1

Caenorhabditis elegans

Enables GTPase activator activity. Predicted to be involved in signal transduction. Expressed in GLRL; GLRR; coelomocyte; excretory cell; and uterine seam cell. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome and coronary artery disease. Is an ortholog of human ARHGAP33 (Rho GTPase activating protein 33).

H12D21.10

Caenorhabditis elegans

Predicted to enable protein O-acetylglucosaminyltransferase activity. Predicted to be involved in protein O-GlcNAcylation via threonine. Predicted to be located in endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Is an ortholog of human EOGT (EGF domain specific O-linked N-acetylglucosamine transferase).

F46H5.4

Caenorhabditis elegans

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase-mediated signal transduction. Human ortholog(s) of this gene implicated in several diseases, including Adams-Oliver syndrome; developmental and epileptic encephalopathy 23; and gastrointestinal system cancer (multiple). Is an ortholog of human DOCK8 (dedicator of cytokinesis 8).

DOCK6-AS1

Homo sapiens

ASSOCIATED WITH Adams-Oliver syndrome; Adams-Oliver Syndrome 1; Adams-Oliver Syndrome 2

T13G4.4

Caenorhabditis elegans

Predicted to enable S-adenosylmethionine-homocysteine S-methyltransferase activity. Predicted to be involved in S-methylmethionine cycle and methionine biosynthetic process.

gst-34

Caenorhabditis elegans

Predicted to enable glutathione transferase activity. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).

W10C8.4

Caenorhabditis elegans

Predicted to enable glutathione transferase activity. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).

gst-35

Caenorhabditis elegans

Predicted to enable glutathione transferase activity. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3).

NALT1

Homo sapiens

ASSOCIATED WITH Adams-Oliver Syndrome 5; INTERACTS WITH butan-1-ol; DDE; triclosan

LINC01451

Homo sapiens

ASSOCIATED WITH Adams-Oliver Syndrome 5; INTERACTS WITH 2-hydroxypropanoic acid; rac-lactic acid