uaf-2

Caenorhabditis elegans

Enables pre-mRNA 3'-splice site binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of U2AF complex and spliceosomal complex. Is an ortholog of human U2AF1 (U2 small nuclear RNA auxiliary factor 1) and U2AF1L4 (U2 small nuclear RNA auxiliary factor 1 like 4).

Luc7l3

Homo sapiens

This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009]

rsp-3

Caenorhabditis elegans

Predicted to enable RNA binding activity. Involved in embryo development. Predicted to be located in nuclear speck. Expressed in PVDL; PVDR; and gonad. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); lung non-small cell carcinoma (multiple); and urinary system cancer (multiple). Is an ortholog of human SRSF1 (serine and arginine rich splicing factor 1).

Srsf5

Homo sapiens

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Srsf3

Homo sapiens

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene. [provided by RefSeq, Sep 2010]

sfa-1

Caenorhabditis elegans

Predicted to enable mRNA binding activity. Involved in alternative mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Is an ortholog of human SF1 (splicing factor 1).

Zdhhc3

Mus musculus

PHENOTYPE: Mice homozygous for a null allele exhibit decreased male body weight and reduced palmitoylation of the gamma2 subunit of GABA type A receptors and of GAP-43 in brain. Primary cultured neurons show reduced accumulation of GABA_ARs at synapses and receptor-dependent presynaptic innervation. [provided by MGI curators]

Zdhhc7

Mus musculus

PHENOTYPE: Mice homozygous for a null allele appear behaviorally and physically normal and show no alterations in palmitoylation of the gamma2 subunit of GABA type A receptors (GABA_ARs), of GAP-43 and of the AMPA receptor subunits GluA2/3 in whole brain extracts. [provided by MGI curators]

Srsf7

Homo sapiens

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an N-terminal RNA recognition motif (RRM) for binding RNA and a C-terminal RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2018]

Srsf9

Homo sapiens

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two pseudogenes, one on chromosome 15 and the other on chromosome 21, have been found for this gene. [provided by RefSeq, Sep 2010]