- WBPaper00046421:cdc-48.2(tm659)_upregulated
Data are presented as mean SEM of at least three separate experiments if not specified otherwise and compared with multiple t-test corrected using the Holm-Sidak method for C. elegans experiments or the one-way analysis of variance (ANOVA) followed by Dunnett's multiple comparison tests for experiments on mammalian cells. The significance was set at P value < 0.05. All statistical analyses were performed using GraphPad Prism (version 6) statistical software (GraphPad Software; San Diego).
Proteins that showed significantly increased expression in cdc-48.2 (EM2[dpy-5(e907); cdc-48.2(tm659); sIs13872[ckb-2p::gfp, pCeh361]]) comparing to in WT (BC14636[dpy-5(e907); sIs13872[ckb-2p::gfp, pCeh361]]) upon tunicamycin treatment.
- WBPaper00030839:Larval_A_Class
A two-class unpaired analysis of the data was performed to identify genes that differ by >= 1.5-fold from the reference at a FDR of <1% for the larval pan-neural, embryonic pan-neural, and larval A-class motor neuron datasets.
Larval A-class motor neuron enriched genes.
- WBPaper00030839:Embryo_A_Class
A two-class unpaired analysis of the data was performed to identify genes that differ by >= 1.5-fold from the reference at a FDR of <1% for the larval pan-neural, embryonic pan-neural, and larval A-class motor neuron datasets.
Embryonic A-class motor neuron enriched genes.
- WBPaper00032454:IR_upregulated
To identify differentially expressed genes, gene expression intensity was compared using a moderated t-test and a Bayes smoothing approach developed for a low number of replicates.
Genes up-regulated following ionizing radiation (IR) treatment.
- WBPaper00065746:tmc-1(rg1003)_upregulated
DESeq2. The genes with a fold change >= 2 and a false discovery rate (FDR) < 0.05 in a comparison were identified as significant DEGs.
Transcripts that showed significantly increased expression in tmc-1(rg1003) comparing to in N2.
- WBPaper00036464:S.aureus-RN6390_regulated
The two conditions were then compared in Resolver to determine fold change for each probe set and a p-value, using a modified t test. Genes with a 2-fold or greater fold change and a p-value ,0.01 were considered differentially expressed.
Genes with altered expression after 8 h S. aureus infection.
- WBPaper00065746:eat-2(ad1113)_downregulated
DESeq2. The genes with a fold change >= 2 and a false discovery rate (FDR) < 0.05 in a comparison were identified as significant DEGs.
Transcripts that showed significantly decreased expression in eat-2(ad1113) comparing to in N2.
- WBPaper00065746:tmc-1(rg1003)_downregulated
DESeq2. The genes with a fold change >= 2 and a false discovery rate (FDR) < 0.05 in a comparison were identified as significant DEGs.
Transcripts that showed significantly decreased expression in tmc-1(rg1003) comparing to in N2.
- WBPaper00065746:eat-2(ad1113)_upregulated
DESeq2. The genes with a fold change >= 2 and a false discovery rate (FDR) < 0.05 in a comparison were identified as significant DEGs.
Transcripts that showed significantly increased expression in eat-2(ad1113) comparing to in N2.