- WBPaper00030839:Embryo_Pan_Neuronal
A two-class unpaired analysis of the data was performed to identify genes that differ by >= 1.5-fold from the reference at a FDR of <1% for the larval pan-neural, embryonic pan-neural, and larval A-class motor neuron datasets.
Embryonic Pan-neural Enriched Genes.
- WBPaper00030839:Larval_Pan_Neuronal
A two-class unpaired analysis of the data was performed to identify genes that differ by >= 1.5-fold from the reference at a FDR of <1% for the larval pan-neural, embryonic pan-neural, and larval A-class motor neuron datasets.
Larval Pan-neural Enriched Genes.
- WBPaper00030839:Embryo_A_Class
A two-class unpaired analysis of the data was performed to identify genes that differ by >= 1.5-fold from the reference at a FDR of <1% for the larval pan-neural, embryonic pan-neural, and larval A-class motor neuron datasets.
Embryonic A-class motor neuron enriched genes.
- WBPaper00030839:Larval_A_Class
A two-class unpaired analysis of the data was performed to identify genes that differ by >= 1.5-fold from the reference at a FDR of <1% for the larval pan-neural, embryonic pan-neural, and larval A-class motor neuron datasets.
Larval A-class motor neuron enriched genes.
- WBPaper00031532:Larva_Pan_Neuronal_Enriched
To identify differentially expressed transcripts, normalized intensity values from the pan-neural data sets were compared to a reference (from all larval cells) using Significance Analysis of Microarray software (SAM). A two class unpaired analysis of the data was performed to identify neuron-enriched genes. Pan-neural enriched transcripts in the IVT and WT-Pico-derived data set were defined as 1.5X elevated vs the reference at a False Discovery Rate (FDR) = 3%.
WT-Pico Pan-neural Enriched Genes, with genes found multiple times in a single dataset removed (without dups).
- WBPaper00031532:Larva_Pan_Neuronal_Depleted
To identify differentially expressed transcripts, normalized intensity values from the pan-neural data sets were compared to a reference (from all larval cells) using Significance Analysis of Microarray software (SAM). A two class unpaired analysis of the data was performed to identify neuron-enriched genes. Pan-neural enriched transcripts in the IVT and WT-Pico-derived data set were defined as 1.5X elevated vs the reference at a False Discovery Rate (FDR) = 3%.
WT-Pico Pan-neural Depleted Genes, with genes found multiple times in a single dataset removed (without dups).
- WBPaper00062118:neural-HSF-1_downregulated
DESeq2 v1.22.2, p-value < 0.05 and fold change > 2.
Transcripts that showed significantly decreased expression in strain AGD1289 with pan-neuronall expression of HSF-1, comparing to in N2 animals.
- WBPaper00062118:neural-HSF-1_upregulated
DESeq2 v1.22.2, p-value < 0.05 and fold change > 2.
Transcripts that showed significantly increased expression in strain AGD1289 with pan-neuronall expression of HSF-1, comparing to in N2 animals.
- WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
edgeR p-value < 0.01 and fold change > 4.
Transcripts that showed significantly increased expression in animals with pan-neuronal expression of human alpha-Synuclein(A53T) (aex-3p-alpha-syn (A53T)), comparing to in N2 animals.