WBPaper00058942:henn-1(pk2295)_upregulated

Differential expression analysis, including fold change and p value calculation, was done using DESeq2 v.1.18.1 with the Benjamin Hochberg multiple test correction applied (FDR = 0.05). mRNAs significantly upregulated >1.3 fold in henn-1(pk2295) gonads comparing to in N2 gonads 68 - 70 hours after L1 larva stage.

WBPaper00058942:henn-1(pk2295)_downregulated

Differential expression analysis, including fold change and p value calculation, was done using DESeq2 v.1.18.1 with the Benjamin Hochberg multiple test correction applied (FDR = 0.05). mRNAs significantly downregulated >1.3 fold in henn-1(pk2295) gonads comparing to in N2 gonads 68 - 70 hours after L1 larva stage.

WBPaper00051425:CB_L1_vs_embryo_upregulated

Benjamin and Hochberg corrected p-value < 0.05. C.briggsae proteins that showed significantly increased at L1 larva stage than in emrbyo.

WBPaper00051425:CB_L4_vs_embryo_upregulated

Benjamin and Hochberg corrected p-value < 0.05. C.briggsae proteins that showed significantly increased at L4 larva stage than in emrbyo.

WBPaper00051425:CB_L4_vs_embryo_downregulated

Benjamin and Hochberg corrected p-value < 0.05. C.briggsae proteins that showed significantly decreased at L4 larva stage than in emrbyo.

WBPaper00051425:CB_L1_vs_embryo_downregulated

Benjamin and Hochberg corrected p-value < 0.05. C.briggsae proteins that showed significantly decreased at L1 larva stage than in emrbyo.

WBPaper00038172:tax-6null_down_regulated

To identify genes that were significantly differentially expressed between each mutant and the control, linear modelling and empirical Bayes analysis was performed using the limma package. Limma computes an empirical Bayes adjustment for the t-test (moderated t-statistic), which is more robust than the standard two-sample t-test comparisons. To correct for multiple testing, Benjamin and Hochbergs method to control for false discovery rate was used. Genes with an adjusted P value of 0.05 or smaller and a fold-change in expression larger than twofold were considered differentially expressed. Genes down regulated in tax-6(ok2065) comparing to in N2.

WBPaper00062684:pathogen_downregulated_N2

DESeq2 (v.3.1.0), adjusted P-value < 0.05 and fold change >= 2. Transcripts in N2 animals that showed significantly decreased expression across all pathogens (S. epidermidis, P. rettgeri, P. aeruginosa, or S. aureus vs. OP50)

WBPaper00062684:pathogen_upregulated_CB4856

DESeq2 (v.3.1.0), adjusted P-value < 0.05 and fold change >= 2. Transcripts in CB4856 animals that showed significantly increased expression across all pathogens (S. epidermidis, P. rettgeri, P. aeruginosa, or S. aureus vs. OP50)

WBPaper00062684:pathogen_upregulated_N2

DESeq2 (v.3.1.0), adjusted P-value < 0.05 and fold change >= 2. Transcripts in N2 animals that showed significantly increased expression across all pathogens (S. epidermidis, P. rettgeri, P. aeruginosa, or S. aureus vs. OP50)