WBPaper00059426:Ag-nanoparticles_downregulated

edgeR, fold change > 2 (set by curator), FDR < 0.05. Transcripts that showed significantly decreased expression after exposed to 10ug per ml Ag nanoparticles from L1 larva to 1-day post L4 adult hermaphrodite stage.

WBPaper00059426:Ag-nanoparticles_upregulated

edgeR, fold change > 2 (set by curator), FDR < 0.05. Transcripts that showed significantly increased expression after exposed to 10ug per ml Ag nanoparticles from L1 larva to 1-day post L4 adult hermaphrodite stage.

WBPaper00049311:Ag-MNP_regulated

Data were screened for differences of each treatment (Ag-MNP, sAg-MNP, and AgNO3) from control using one-way ANOVA with contrasts. The false discovery rate (FDR) threshold was set at 0.2 and the fold change was required to be greater than 1.5, and a P-value <= 0.05. The FDR of 0.2 was selected to balance the protection against false positives while minimizing the rate of false negatives. Using Partek, genes that were significantly different from control in at least one treatment were then analyzed using agglomerative hierarchical cluster analysis (HCA). HCA is a 2-Pass clustering method; the first pass is a K-means clustering and in the second pass the K-means clusters are joined by agglomerative clustering. Transcripts that showed significantly altered expression after 48 hour exposure to Ag-MNP.

WBPaper00049311:AgNO3_regulated

Data were screened for differences of each treatment (Ag-MNP, sAg-MNP, and AgNO3) from control using one-way ANOVA with contrasts. The false discovery rate (FDR) threshold was set at 0.2 and the fold change was required to be greater than 1.5, and a P-value <= 0.05. The FDR of 0.2 was selected to balance the protection against false positives while minimizing the rate of false negatives. Using Partek, genes that were significantly different from control in at least one treatment were then analyzed using agglomerative hierarchical cluster analysis (HCA). HCA is a 2-Pass clustering method; the first pass is a K-means clustering and in the second pass the K-means clusters are joined by agglomerative clustering. Transcripts that showed significantly altered expression after 48 hour exposure to AgNO3.

WBPaper00049311:sAg-MNP_regulated

Data were screened for differences of each treatment (Ag-MNP, sAg-MNP, and AgNO3) from control using one-way ANOVA with contrasts. The false discovery rate (FDR) threshold was set at 0.2 and the fold change was required to be greater than 1.5, and a P-value <= 0.05. The FDR of 0.2 was selected to balance the protection against false positives while minimizing the rate of false negatives. Using Partek, genes that were significantly different from control in at least one treatment were then analyzed using agglomerative hierarchical cluster analysis (HCA). HCA is a 2-Pass clustering method; the first pass is a K-means clustering and in the second pass the K-means clusters are joined by agglomerative clustering. Transcripts that showed significantly altered expression after 48 hour exposure to sAg-MNP.