Expr2285

Both TU#677 and TU#676 are expressed exclusively in the six touch receptor neurons, as identified by their positions and projections, throughout development, beginning in embryogenesis.

Expr268

A long transcript mec-9lacZ fusion (TU#165) was expressed only in the 6 touch cells and occasionally in the PVD cells. A fusion specific to the short transcript (TU#160) was expressed in about 25 cells in the head and 50 cells in the ventral cord. Replacing lacZ with the gfp coding region, which permitted visualization of cell processes (in fusion TU#163), showed that the expressing cells were neurons. An integrated line (uIs10) with a mec-9lacZ fusion (TU#171) designed to be expressed in both transcripts was expressed in both sets of cells.

Expr11808

A fusion containing 583 bp upstream of the translation start site (TU#276) directed expression to the six touch cells.

Expr11807

A construct containing only 169 bp of upstream sequence (TU#190) shows the normal expression pattern in ALM, AVM, PLM, PVM.

Expr1624

lacZ and gfp fusions with the mec-5 promoter (TU#233 and TU#234, respectively) and a lacZ fusion with part of the mec-5 coding sequence and a sequence for a synthetic transmembrane domain (TU#235) gave the same pattern of expression with strong expression by hypodermal cells. In newly hatched animals, MEC-5 is strongly expressed by seam cells (epidermal stem cells) along the body and by hypodermal cells in the head. As the animals mature and the seam cells divide, MEC-5 is expressed by both seam cells and their progeny, but at a lower level than in newly hatched larvae. In early L2 larvae, staining is also seen in the cells of the ventral hypodermis. Strong staining is limited to the head in adults.

Expr15232

Unc-64 isoform A and B.

Expr4500

Expression observed in B, B.a and B.p.

Expr14177

ASK, ASI, vulval cells, B and Y rectal epithelial cells

Expr8518

DAF-19A/B were expressed only in nonciliated neurons and not in ciliated sensory neurons. In summary, DAF-19A/B are expressed in 200 to 240 nonciliated neurons.

Expr13384

The sgk-1 isoform B promoter drives expression in the intestine.