Expr15683

The expression pattern of endogenously tagged LIN-28::GFP is similar to that reported previously for a transgene expressing tagged LIN-28 (Moss et al., 1997): LIN-28 is highly expressed in embryos and in L1- and L2-stage larvae and is diminished at subsequent larval stages.

Expr14648

Consistent with previous reporter gene analysis (Moss et al., 1997), we found that a fosmid-based reporter construct of the lin-28 gene is expressed very broadly in the nervous system in a sexually non-dimorphic manner and downregulated by the end of the L2 stage.

Expr14270

The endogenous lin-28 promoter drives lin-28::GFP expression in neurons and hypodermis, where lin-28 is known to be expressed (Moss et al., 1997). Using spinning disk microscopy we also detected lin-28p::lin-28::GFP expression in Z1 and Z4 cells, which are precursors of somatic gonadal tissues.