ari-1 is consistently expressed in the germline of adults and larvae. Levels of ari-1 mRNA were relatively modest compared to that of a positive control that is expressed at high levels in this tissue (hmg-3).
Expression of ARI-1 is dynamic during early embryonic development, with ubiquitous somatic expression occurring between the 50- and 200-cell stage. By the late proliferative phase of embryogenesis (~400 - 500 cells), expression is reduced in most nuclei but is maintained at high levels in muscle precursors. Similar to later embryonic and larval time points, expression in the early embryo is always observed in both the nucleus and cytoplasm of GFP-positive cells.