Expr12427
Immunohistochemistry revealed that HDA-3 is ubiquitously expressed. Costaining with an OSM-10 antisera that recognizes an endogenous protein expressed in the ASH (Hart et al., 1999) confirmed that HDA-3 protein is found in the ASH neurons. Endogenous HDA-3 predominantly localizes to the nucleus in C. elegans, where it is likely to function in transcriptional regulation.