B-cell lymphoma

A non-Hodgkin lymphoma that has_material_basis_in B cells.

T-cell non-Hodgkin lymphoma

A non-Hodgkin lymphoma of T-cell lineage.

anaplastic large cell lymphoma

A non-Hodgkin lymphoma involving aberrant T-cells.

mature T-cell and NK-cell lymphoma

A T-cell non-Hodgkin lymphoma that has_material_basis_in mature T lymphocytes and natural killer cells.

primary cutaneous gamma-delta T-cell lymphoma

A primary cutaneous T-cell non-Hodgkin lymphoma that is characterized by the clonal cutaneous proliferation of activated mature gamma-delta T cells with a cytotoxic phenotype.

grade III lymphomatoid granulomatosis

A lymphomatoid granulomatosis that is characterized by the presence of aggregates of neoplastic large B-lymphocytes, usually admixed with pleomorphic and Hodgkin-like cells, in a background of chronic inflammation. Necrotic changes are present and are usually extensive.

lymphoproliferative syndrome 1

A lymphoproliferative syndrome characterized by autosomal recessive inheritance, early childhood onset of Epstein-Barr virus-associated immune dysregulation typically manifesting as lymphoma, lymphomatoid granulomatosis, hemophagocytic lymphohistiocytosis, Hodgkin disease, and-or hypogammaglobulinemia and that has_material_basis_in homozygous mutation in the ITK gene on chromosome 5q32.

DNA ligase IV deficiency

A combined T cell and B cell immunodeficiency that has_material_basis_in a mutation in the LIG4 gene, a DNA ligase, encoding a protein essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). Patients present with immunodeficiency and developmental and growth delay.