C. elegans gene expression in response to Y. pestis KIM5 infection

The response of the nematode C. elegans to Y. pestis infection was evaluated by gene expression profiling. A synchronized population of nematodes were exposed to Y. pestis KIM5 for 24h. Transcript levels from Y. pestis-treated animals were compared with animals maintained on relatively nonpathogenic E. coli OP50 for 24h.

Using RNA-seq to identify transcriptional targets of MAB-5 in C. elegans

Illumina Genome Analyzer IIx paired end sequencing; C. elegans wild-type strain LE2544 (lqIs80 IV; lqIs58 V), early L1 larvae transcriptome (replicate library 2, lane 1)

Using RNA-seq to identify transcriptional targets of MAB-5 in C. elegans

Illumina Genome Analyzer IIx paired end sequencing; C. elegans wild-type strain LE2544 (lqIs80 IV; lqIs58 V), early L1 larvae transcriptome (replicate library 3, lane 1)

Using RNA-seq to identify transcriptional targets of MAB-5 in C. elegans

Illumina Genome Analyzer IIx paired end sequencing; C. elegans wild-type strain LE2544 (lqIs80 IV; lqIs58 V), early L1 larvae transcriptome (replicate library 4, lane 1)

Using RNA-seq to identify transcriptional targets of MAB-5 in C. elegans

Illumina Genome Analyzer IIx paired end sequencing; C. elegans wild-type strain LE2544 (lqIs80 IV; lqIs58 V), early L1 larvae transcriptome (replicate library 1, lane 2)

Using RNA-seq to identify transcriptional targets of MAB-5 in C. elegans

Illumina Genome Analyzer II paired end sequencing; C. elegans wild-type strain LE2544 (lqIs80 IV; lqIs58 V), early L1 larvae transcriptome (replicate library 1, lane 1)

Using RNA-seq to identify transcriptional targets of MAB-5 in C. elegans

Illumina Genome Analyzer IIx paired end sequencing; C. elegans wild-type strain LE2544 (lqIs80 IV; lqIs58 V), early L1 larvae transcriptome (replicate library 2, lane 2)

Using RNA-seq to identify transcriptional targets of MAB-5 in C. elegans

Illumina Genome Analyzer IIx paired end sequencing; C. elegans wild-type strain LE2544 (lqIs80 IV; lqIs58 V), early L1 larvae transcriptome (replicate library 3, lane 2)

Using RNA-seq to identify transcriptional targets of MAB-5 in C. elegans

Illumina Genome Analyzer IIx paired end sequencing; C. elegans wild-type strain LE2544 (lqIs80 IV; lqIs58 V), early L1 larvae transcriptome (replicate library 4, lane 2)

Using RNA-seq to identify transcriptional targets of MAB-5 in C. elegans

Illumina Genome Analyzer IIx paired end sequencing; C. elegans loss-of-function strain LE2962 (mab-5(e1239) III; lqIs80 IV; lqIs58 V), early L1 larvae transcriptome (replicate library 1, lane 2)