- strain: GW637
Caenorhabditis elegans - expression cluster: WBPaper00058942:henn-1(pk2295)_upregulated
Differential expression analysis, including fold change and p value calculation, was done using DESeq2 v.1.18.1 with the Benjamin Hochberg multiple test correction applied (FDR = 0.05).
mRNAs significantly upregulated >1.3 fold in henn-1(pk2295) gonads comparing to in N2 gonads 68 - 70 hours after L1 larva stage.
- expression cluster: WBPaper00058942:henn-1(pk2295)_downregulated
Differential expression analysis, including fold change and p value calculation, was done using DESeq2 v.1.18.1 with the Benjamin Hochberg multiple test correction applied (FDR = 0.05).
mRNAs significantly downregulated >1.3 fold in henn-1(pk2295) gonads comparing to in N2 gonads 68 - 70 hours after L1 larva stage.
- expression cluster: WBPaper00045263:ProLongevity-mtROS_upregulated
Comparisons of each genotype were compared to the wild-type using the Empirical Base (Wright & Simon) algorithm and fold changes were represented on a log2 scale. A threshold of p < 0.05 and a fold change of 1.3 (log2) was set to determine differentially expressed targets.
Transcripts with significantly increased expression under all of these conditions
- expression cluster: WBPaper00045263:ProLongevity-mtROS_downregulated
Comparisons of each genotype were compared to the wild-type using the Empirical Base (Wright & Simon) algorithm and fold changes were represented on a log2 scale. A threshold of p < 0.05 and a fold change of 1.3 (log2) was set to determine differentially expressed targets.
Transcripts with significantly decreased expression under all of these conditions
- expression cluster: WBPaper00045263:0.1mM-paraquat_upregulated
Comparisons of each genotype were compared to the wild-type using the Empirical Base (Wright & Simon) algorithm and fold changes were represented on a log2 scale. A threshold of p < 0.05 and a fold change of 1.3 (log2) was set to determine differentially expressed targets.
Transcripts with significantly increased expression after treatment with 0.1mM paraquat vs. control
- expression cluster: WBPaper00045263:isp-1(qm150)_downregulated
Comparisons of each genotype were compared to the wild-type using the Empirical Base (Wright & Simon) algorithm and fold changes were represented on a log2 scale. A threshold of p < 0.05 and a fold change of 1.3 (log2) was set to determine differentially expressed targets.
Transcripts with significantly decreased expression in isp-1(qm150) vs. N2, and in isp-1(qm150)ced-4(n1162) vs. ced-4(n1162).
- expression cluster: WBPaper00045263:0.1mM-paraquat_downregulated
Comparisons of each genotype were compared to the wild-type using the Empirical Base (Wright & Simon) algorithm and fold changes were represented on a log2 scale. A threshold of p < 0.05 and a fold change of 1.3 (log2) was set to determine differentially expressed targets.
Transcripts with significantly decreased expression after treatment with 0.1mM paraquat vs. control
- expression cluster: WBPaper00045263:nuo-6(qm200)_upregulated
Comparisons of each genotype were compared to the wild-type using the Empirical Base (Wright & Simon) algorithm and fold changes were represented on a log2 scale. A threshold of p < 0.05 and a fold change of 1.3 (log2) was set to determine differentially expressed targets.
Transcripts with significantly increased expression in nuo-6(qm200) vs. N2, and in nuo-6(qm200);ced-4(n1162) vs. ced-4(n1162).
- expression cluster: WBPaper00045263:isp-1(qm150)_upregulated
Comparisons of each genotype were compared to the wild-type using the Empirical Base (Wright & Simon) algorithm and fold changes were represented on a log2 scale. A threshold of p < 0.05 and a fold change of 1.3 (log2) was set to determine differentially expressed targets.
Transcripts with significantly increased expression in isp-1(qm150) vs. N2, and in isp-1(qm150) ced-4(n1162) vs. ced-4(n1162).