wbp-11

Caenorhabditis elegans

Predicted to be involved in RNA processing. Is an ortholog of human WBP11 (WW domain binding protein 11).

wac-1.2

Caenorhabditis elegans

Enriched in several structures, including ABalappaap; ABplapappp; ABplapppaa; ABprapppaa; and germ line based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cua-1; atfs-1; and rpl-5 based on microarray; tiling array; and RNA-seq studies. Is affected by five chemicals including rotenone; stavudine; and rifampin based on RNA-seq studies. Human ortholog(s) of this gene implicated in DeSanto-Shinawi syndrome. Is predicted to encode a protein with the following domains: WW domain superfamily and WW domain. Is an ortholog of human WAC (WW domain containing adaptor with coiled-coil). Human WAC enables RNA polymerase II complex binding activity and chromatin binding activity.

wbp-4

Caenorhabditis elegans

Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing. Predicted to be part of precatalytic spliceosome. Is an ortholog of human WBP4 (WW domain binding protein 4).

DC2.5

Caenorhabditis elegans

Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Is an ortholog of human WWOX (WW domain containing oxidoreductase).

Y92H12BM.1

Caenorhabditis elegans

Enriched in ABplpppaaa; ABprpppaaa; AVJ; head mesodermal cell; and motor neurons based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including cyc-1; nuo-6; and etr-1 based on microarray and RNA-seq studies. Is affected by six chemicals including rotenone; rifampin; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: WW domain superfamily; WW domain; and Phosphorylation site. Is an ortholog of human ARHGAP39 (Rho GTPase activating protein 39).

dhs-8

Caenorhabditis elegans

Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Is an ortholog of human WWOX (WW domain containing oxidoreductase).

F32A5.8

Caenorhabditis elegans

Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Is an ortholog of human WWOX (WW domain containing oxidoreductase).

K10H10.6

Caenorhabditis elegans

Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Is an ortholog of human WWOX (WW domain containing oxidoreductase).

E04F6.15

Caenorhabditis elegans

Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Is an ortholog of human WWOX (WW domain containing oxidoreductase).

sav-1

Caenorhabditis elegans

Predicted to enable molecular adaptor activity. Predicted to be involved in hippo signaling; negative regulation of cell population proliferation; and positive regulation of apoptotic process. Predicted to be located in cytosol. Is an ortholog of human SAV1 (salvador family WW domain containing protein 1).