npp-14

Caenorhabditis elegans

Enables caspase binding activity. Involved in negative regulation of execution phase of apoptosis. Predicted to be located in nuclear membrane. Predicted to be part of nuclear pore. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; acute myeloid leukemia; and brain disease. Is an ortholog of human NUP214 (nucleoporin 214).