Predicted to enable protein tyrosine phosphatase activity. Involved in positive regulation of axon regeneration. Located in axon. Expressed in DD neuron; VD neuron; head; and intestinal muscle. Is an ortholog of human TNS1 (tensin 1).
Predicted to enable calcium ion binding activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Expressed in several structures, including QL; QR; VD neuron; non-striated muscle; and rectal gland cell. Human ortholog(s) of this gene implicated in carcinoma (multiple); colorectal cancer; and spinocerebellar ataxia 45. Is an ortholog of human FAT1 (FAT atypical cadherin 1); FAT2 (FAT atypical cadherin 2); and FAT3 (FAT atypical cadherin 3).
Enriched in VD neuron and VD12 based on single-cell RNA-seq studies. Is affected by several genes including etr-1; rrf-3; and crh-1 based on microarray and RNA-seq studies. Is affected by paraquat based on RNA-seq studies.
Enriched in VD neuron and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including etr-1; dpy-21; and glp-1 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies.