gene: hst-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable [heparan sulfate]-glucosamine N-sulfotransferase activity and deacetylase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 46. Is an ortholog of several human genes including NDST1 (N-deacetylase and N-sulfotransferase 1); NDST2 (N-deacetylase and N-sulfotransferase 2); and NDST3 (N-deacetylase and N-sulfotransferase 3).
gene: elpc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable tRNA binding activity. Involved in several processes, including gamete generation; gene expression; and olfactory learning. Located in cytoplasm; neuron projection; and neuronal cell body. Expressed in CAN; HSN; pharynx; sensory neurons; and vulva. Used to study Riley-Day syndrome. Human ortholog(s) of this gene implicated in several diseases, including Riley-Day syndrome; bone structure disease (multiple); and medulloblastoma. Is an ortholog of human ELP1 (elongator acetyltransferase complex subunit 1).