AMH57

Caenorhabditis elegans

AMH91

Caenorhabditis elegans

AMH59

Caenorhabditis elegans

LX837

Caenorhabditis elegans

arp-1

Caenorhabditis elegans

Part of dynactin complex. Human ortholog(s) of this gene implicated in Down syndrome and colon cancer. Is an ortholog of human ACTR1A (actin related protein 1A).

fecl-1

Caenorhabditis elegans

Predicted to enable ferrochelatase activity. Predicted to be involved in heme biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in colon adenocarcinoma; cutaneous porphyria; and erythropoietic protoporphyria. Is an ortholog of human FECH (ferrochelatase).

chaf-1

Caenorhabditis elegans

Predicted to be involved in nucleosome assembly. Predicted to be located in nucleus. Predicted to be part of CAF-1 complex. Human ortholog(s) of this gene implicated in several diseases, including colon cancer; neuroblastoma; and systemic lupus erythematosus. Is an ortholog of human CHAF1A (chromatin assembly factor 1 subunit A).

pfas-1

Caenorhabditis elegans

Predicted to enable phosphoribosylformylglycinamidine synthase activity. Predicted to be involved in purine nucleotide biosynthetic process. Predicted to be located in cytoplasm. Expressed in intestinal cell. Human ortholog(s) of this gene implicated in colon adenocarcinoma; hepatocellular carcinoma; and renal cell carcinoma. Is an ortholog of human PFAS (phosphoribosylformylglycinamidine synthase).

hst-3.2

Caenorhabditis elegans

Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi lumen. Expressed in epithelial cell; hypodermis; neurons; and vulva. Human ortholog(s) of this gene implicated in several diseases, including colon cancer; hereditary angioedema; and lung non-small cell carcinoma. Is an ortholog of human HS3ST2 (heparan sulfate-glucosamine 3-sulfotransferase 2).

abhd-5.1

Caenorhabditis elegans

Predicted to enable carboxylic ester hydrolase activity and lysophosphatidic acid acyltransferase activity. Predicted to be involved in lipid homeostasis and phosphatidic acid biosynthetic process. Predicted to be located in lipid droplet and mitochondrion. Human ortholog(s) of this gene implicated in Chanarin-Dorfman syndrome; autosomal recessive congenital ichthyosis 1; and colon adenocarcinoma. Is an ortholog of human ABHD4 (abhydrolase domain containing 4, N-acyl phospholipase B) and ABHD5 (abhydrolase domain containing 5, lysophosphatidic acid acyltransferase).