- strain: MBA1192
Caenorhabditis elegans - strain: MT26375
Caenorhabditis elegans - gene: spk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein serine/threonine kinase activity. Involved in embryo development. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including gonad and tail. Is an ortholog of human SRPK1 (SRSF protein kinase 1); SRPK2 (SRSF protein kinase 2); and SRPK3 (SRSF protein kinase 3).
- gene: tsr-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in protein import into nucleus. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 2. Is an ortholog of human TNPO3 (transportin 3).
- strain: MT23338
Caenorhabditis elegans - gene: rsp-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Human ortholog(s) of this gene implicated in autism spectrum disorder and myelodysplastic syndrome. Is an ortholog of human SREK1 (splicing regulatory glutamic acid and lysine rich protein 1).
- gene: rsp-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); hematologic cancer (multiple); and lung cancer (multiple). Is an ortholog of human SRSF2 (serine and arginine rich splicing factor 2).
- gene: rsp-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity. Involved in developmental process involved in reproduction; nematode larval development; and regulation of growth rate. Located in nucleus. Expressed widely. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; carcinoma (multiple); and proliferative diabetic retinopathy. Is an ortholog of human SRSF5 (serine and arginine rich splicing factor 5) and SRSF6 (serine and arginine rich splicing factor 6).