lpd-5

Caenorhabditis elegans

Involved in lipid storage. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in Leigh disease and nuclear type mitochondrial complex I deficiency 1. Is an ortholog of human NDUFS4 (NADH:ubiquinone oxidoreductase subunit S4).

nduf-7

Caenorhabditis elegans

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in aerobic respiration; electron transport coupled proton transport; and mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex I. Expressed in intestine. Human ortholog(s) of this gene implicated in bipolar disorder; developmental disorder of mental health; and nuclear type mitochondrial complex I deficiency 3. Is an ortholog of human NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7).

nuo-5

Caenorhabditis elegans

Predicted to enable 4 iron, 4 sulfur cluster binding activity; metal ion binding activity; and oxidoreductase activity, acting on NAD(P)H. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in cellular respiration. Predicted to be located in mitochondrion. Predicted to be part of respiratory chain complex I. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 5. Is an ortholog of human NDUFS1 (NADH:ubiquinone oxidoreductase core subunit S1).

ndus-8

Caenorhabditis elegans

Predicted to enable 4 iron, 4 sulfur cluster binding activity; NADH dehydrogenase (ubiquinone) activity; and metal ion binding activity. Predicted to contribute to NADH dehydrogenase activity. Involved in mitochondrial electron transport, NADH to ubiquinone and response to xenobiotic stimulus. Located in mitochondrion. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 2. Is an ortholog of human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8).

sdhb-1

Caenorhabditis elegans

Contributes to succinate dehydrogenase (quinone) activity. Predicted to be involved in aerobic respiration and respiratory electron transport chain. Located in mitochondrion. Expressed in head and tail. Used to study paraganglioma. Human ortholog(s) of this gene implicated in several diseases, including Carney-Stratakis syndrome; gastrointestinal stromal tumor; and mitochondrial complex II deficiency. Is an ortholog of human SDHB (succinate dehydrogenase complex iron sulfur subunit B).

cds: ZK973.10

Caenorhabditis elegans

cds: Y43F8B.19

Caenorhabditis elegans

cds: C14E2.4

Caenorhabditis elegans

cds: Y43F8B.4a

Caenorhabditis elegans

cds: Y43F8B.4b

Caenorhabditis elegans