ZM6665

Caenorhabditis elegans

ins-20

Caenorhabditis elegans

Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in head neurons and sensory neurons.

ins-25

Caenorhabditis elegans

Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in motor neurons; nerve ring neurons; and tail neurons.

ins-22

Caenorhabditis elegans

Predicted to be located in extracellular region. Expressed in nervous system; pharynx; rectum; and vulval muscle.

ins-29

Caenorhabditis elegans

Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Expressed in coelomocyte; head neurons; pharynx; and sensory neurons.

fat-2

Caenorhabditis elegans

Enables stearoyl-CoA 9-desaturase activity. Involved in collagen and cuticulin-based cuticle development; fatty acid biosynthetic process; and innate immune response. Predicted to be located in membrane.

trxr-2

Caenorhabditis elegans

Enables thioredoxin-disulfide reductase (NADPH) activity. Predicted to be involved in cell redox homeostasis. Located in mitochondrion. Expressed in intestine; muscle cell; nervous system; and vulva. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in familial glucocorticoid deficiency. Is an ortholog of human TXNRD2 (thioredoxin reductase 2).

cht-1

Caenorhabditis elegans

Enables chitinase activity. Involved in chitin catabolic process and response to fungus. Predicted to be located in extracellular region. Expressed in gonad. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); and lung disease (multiple). Is an ortholog of human CHIA (chitinase acidic).

usp-14

Caenorhabditis elegans

Predicted to enable cysteine-type deubiquitinase activity and proteasome binding activity. Predicted to be involved in protein deubiquitination and regulation of proteasomal protein catabolic process. Predicted to be part of proteasome complex. Is an ortholog of human USP14 (ubiquitin specific peptidase 14).

dbr-1

Caenorhabditis elegans

Predicted to enable RNA lariat debranching enzyme activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in brain disease. Is an ortholog of human DBR1 (debranching RNA lariats 1).