gene: F46H5.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase-mediated signal transduction. Human ortholog(s) of this gene implicated in several diseases, including Adams-Oliver syndrome; developmental and epileptic encephalopathy 23; and gastrointestinal system cancer (multiple). Is an ortholog of human DOCK8 (dedicator of cytokinesis 8).